Fusion proteins comprising coiled-coil structures

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) G01R 33/46 (2006.01)

Patent

CA 2290716

The invention relates to a fusion protein comprising a) a first region capable of forming a coiled-coil structure; and b) a second region not naturally associated with the first region comprising a polypeptide sequence of interest. The fusion protein of the invention is applicable to the production of very small polypeptides in transformed host cells.

La présente invention porte sur une protéine de fusion comprenant: a) une première région capable de former une structure bispiralée; et b) une seconde région non naturellement associée à la première et comprenant une séquence polypeptidique. Cette protèine de fusion peut être utilisée dans la production de très petits polypeptides dans des cellules hôtes transformées.

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