Fusion proteins comprising tumor necrosis factor receptor

Details Fusion proteins comprising tumor necrosis factor receptor Fusion proteins comprising tumor necrosis factor receptor

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) C07K 14/71 (2006.01) C07K 14/715 (2006.01) C07K 19/00 (2006.01) C12N 15/25 (2006.01) C12N 15/28 (2006.01) C12N 15/79 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2133326

Fusion proteins comprise a tumor necrosis factor receptor (TNF-R) polypeptide and at least one additional polypeptide selected from an interleukin-1 receptor (IL-1R) and a second TNF-R polypeptide. One such fusion protein comprise, one IL-1R and two TNF-R polypeptides. The fusion proteins have therapeutic use and may be produced via recombinant DNA technology.

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