A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 38/18 (2006.01)
Patent
CA 2625293
The invention provides compositions, methods, and kits for increasing transport of agents across the blood brain barrier while allowing their activity once across the barrier to remain substantially intact. The agents are transported across the blood brain barrier via one or more endogenous receptor-mediated transport systems. In some embodiments the agents are therapeutic, diagnostic, or research agents.
Cette invention concerne des compositions, des méthodes et des kits permettant d'accroître le transport d'agents à travers la barrière hémato-encéphalique quasiment sans perte substantielle d'activité de ces agents une fois la barrière traversée. Lesdits agents sont transportés au travers le la barrière hépato-encéphalique via un ou plusieurs systèmes de transport induits par des récepteurs endogènes. Dans certains modes de réalisation, les agents sont utilisés à des fins thérapeutique, diagnostique ou de recherche.
Boado Ruben J.
Pardridge William M.
Armagen Technologies Inc.
Gowling Lafleur Henderson Llp
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