Fusion proteins of mannose binding lectins for treatment of...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/47 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2705160

Fusion proteins having sequences that target specific moieties such as carbohydrates, lipids, and/or proteins that are associated with certain cell types and/or pathogens; and a sequence that induces effector function are provided. The disclosure also provides nucleic acids encoding the fusion proteins, as well as pharmaceutical compositions, methods of use, and methods of treating conditions or diseases such as infectious diseases, cancers, immune related disorders and other ailments, that include the fusions proteins described herein.

L'invention concerne des protéines de fusion ayant des séquences qui ciblent des fractions spécifiques telles que des hydrates de carbone, des lipides, et/ou des protéines qui sont associées à certains types de cellule et/ou pathogènes ; et une séquence induisant une fonction effectrice. La description concerne également des acides nucléiques codant les protéines de fusion, ainsi que des compositions pharmaceutiques, des procédés d'utilisation, et des procédés de traitement d'états ou de maladies telles que des maladies infectieuses, des cancers, des troubles de nature immunitaire et autres affections, qui comprennent les protéines de fusion décrites ci-dessus.

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