C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 38/17 (2006.01) A61K 39/04 (2006.01) A61K 49/00 (2006.01) C07K 14/35 (2006.01) C07K 19/00 (2006.01) C12N 15/31 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2413959
The present invention relates to compositions and fusion proteins containing at least two Mycobacterium sp. antigens, and nucleic acids encoding such compositions and fusion proteins. The compositions of the invention increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection.
L'invention porte sur des compositions et des protéines de fusion contenant au moins deux antigènes du Mycobacterium sp., et sur les acides nucléiques codant pour ces compositions et protéines de fusion, lesdites compositions accroissant la sensibilité sérologique du sérum d'individus infectés par la tuberculose. L'invention porte également sur leurs méthodes d'utilisation à des fins de diagnostic, de traitement et de prévention de la tuberculose.
Alderson Mark
Reed Steven
Skeiky Yasir
Corixa Corporation
Gowling Lafleur Henderson Llp
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