Fusion proteins with glutathione-s-transferase

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

530/15.12, 195/1

C12N 15/62 (2006.01) C07K 14/435 (2006.01) C12N 9/10 (2006.01) C12N 9/96 (2006.01) C12N 15/54 (2006.01)

Patent

CA 1338903

A recombinant DNA molecule comprising a nucleotide sequence which codes an expression for a fusion protein in which a foreign protein or peptide is fused with the enzyme glutathione-S-transferase, is disclosed, as well as expression vectors or host cells containing such a molecule. Optionally, the foreign protein or peptide is fused to the enzyme through a cleavable link. Also disclosed is an expression vector having inserted therein a nucleotide sequence capable of being expressed as the enzyme glutathione-S-transferase followed by at least one restriction endonuclease recognition site for insertion of a nucleotide sequence capable of being expressed as a foreign protein or peptide fused to the glutathione-S-transferase.

567639

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