C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01)
Patent
CA 2728350
The present invention relates to novel oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group, pharmaceutically acceptable salts thereof, methods for preparing the same and pharmaceutical compositions comprising the same. The oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group or the pharmaceutically acceptable salts thereof can be effectively used for the treatment of thromboembolism and tumor as an anticoagulant based on the inhibition of factor Xa.
La présente invention concerne de nouveaux dérivés doxazolidinone avec un groupe amidoxime cyclique ou amidrazone cyclique, des sels pharmaceutiquement acceptables de ceux-ci, des procédés pour préparer ceux-ci et des compositions pharmaceutiques comprenant ceux-ci. Les dérivés doxazolidinone avec un groupe amidoxime cyclique ou amidrazone cyclique ou les sels pharmaceutiquement acceptables de ceux-ci peuvent être efficacement utilisés pour le traitement dune maladie thromboembolique et dune tumeur en tant quanticoagulant basé sur linhibition du facteur Xa.
Baek Sung Yoon
Chae Sang Eun
Cho Young Lag
Jo Sang Hui
Kim Yeon Ok
Fasken Martineau Dumoulin Llp
Legochem Bioscience Ltd.
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