C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/27 (2006.01) C07K 1/00 (2006.01) C07K 14/535 (2006.01) G01N 33/68 (2006.01) G06F 3/14 (2006.01) G06F 17/50 (2006.01) G06T 17/00 (2006.01) A61K 38/00 (2006.01) G06F 19/00 (2006.01)
Patent
CA 2153896
Provided herein are granulocyte colony factor ("G-CSF") analogs, compositions containing such analogs, and related compositions. In another aspect, provided herein are nucleic acids encoding the present analogs or related nucleic acids, related host cells and vectors. In yet another aspect, provided herein are computer programs and apparatuses for expressing the three dimensional structure of G-CSF and analogs thereof. In another aspect, provided herein are methods for rationally designing G-CSF analogs and related compositions. In yet another aspect, provided herein are methods for treatment using the present G-CSF analogs.
On décrit des analogues du facteur stimulant des colonies de granulocytes ("G-CSF"), des compositions contenant ces analogues, ainsi que des compositions relatives. Selon un autre aspect de l'invention, on décrit des acides nucléiques codant lesdits analogues ou des acides nucléiques relatifs, des cellules hôtes et des vecteurs relatifs. Selon un autre aspect, on décrit des programmes et des appareils informatiques permettant d'exprimer la structure tridimensionnelle du G-CSF et de ses analogues. Selon encore un autre aspect, on décrit des méthodes de traitement utilisant les analogues de G-CSF ci-décrits.
Amgen Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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