G immunoglobulin used against anthrax toxins

Details G immunoglobulin used against anthrax toxins G immunoglobulin used against anthrax toxins

C - Chemistry, Metallurgy

07

K

C07K 16/12 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 31/04 (2006.01) C12N 15/13 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2707201

The invention relates to a G-class immunoglobulin (IgG) directed against the protective antigen (PA) of the anthrax toxin, that includes: a light-chain variable region including an amino-acid sequence that is at least 90% identical in terms of amino-acids with the sequence SEQ ID N °1 as defined in the description; and a heavy-chain variable region including an amino acid sequence that is at least 90% identical in terms of amino-acids with the sequence SEQ ID N °2 as defined in the description; characterised in that it consists of an IgG1 or an IgG2.

L'invention concerne une immunoglobuline de classe G (IgG) dirigée contre l'antigène protecteur (PA) de la toxine du charbon, comprenant; une région variable de chaîne légère comprenant une séquence d'acides aminés possédant au moins 90 % d'identité en acides aminés avec la séquence SEQ ID N o1 telle que définie dans la description, et une région variable de chaîne lourde comprenant une séquence d'acides aminés possédant au moins 90% d'identité en acides aminés avec la séquence SEQ ID N o2 telle que définie dans la description, caractérisé en ce qu'il s'agit d'une IgG1 ou d'une IgG2.

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