G protein-coupled glutamate receptors

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12Q 1/02 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) G01N 33/60 (2006.01)

Patent

CA 2098295

Mammalian G protein-coupled glutamate receptors are identified, isolated and purified. The receptors have been cloned, sequenced and expressed by recombinant means. The receptors and antibodies thereto can be used to identify agonists and anta- gonists of G protein-coupled glutamate receptor mediated neuronal excitation and in methods of diagnosis.

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