G protein coupled receptor a4

Details G protein coupled receptor a4 G protein coupled receptor a4

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2284857

A novel G protein coupled receptor family is described, herein called A4. DNA coding for this receptor has been isolated. Methods of producing recombinant cell lines which produce the receptor as a heterologous membrane-bound product are described, as well as other related aspects of the invention, which are of commercial significance, including use of the cell lines for the discovery of therapeutic compounds which modulate the receptor activity.

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