G-protein coupled receptor and method of using same

Details G-protein coupled receptor and method of using same G-protein coupled receptor and method of using same

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2369324

Disclosed is a nucleic acid encoding a novel G-protein coupled receptor and methods of using the same. The novel-G-protein coupled receptor was identified as a member of a set of genes that are differentially expressed in diseased fibroblasts relative to non-diseased fibroblasts. The invention also provides methods for identifying and treating disease based on the set of differentially expressed sequences.

L'invention concerne un acide nucléique codant un nouveau récepteur couplé à la protéine G, et des procédés d'utilisation dudit récepteur. Ce nouveau récepteur couplé à la protéine G a été identifié en tant qu'élément d'un ensemble de gènes exprimés de manière différentielle dans des fibroblastes malades par rapport à des fibroblastes sains. L'invention concerne en outre des procédés d'identification et de traitement d'une maladie utilisant ledit ensemble de séquences exprimées de manière différentielle.

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