G-protein coupled receptor, named 2871 receptor

Details G-protein coupled receptor, named 2871 receptor G-protein coupled receptor, named 2871 receptor

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/16 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2328891

The present invention relates to a newly identified G-protein-coupled receptor. The invention also relates to polynucleotides encoding the receptors. The invention further relates to methods using receptor polypeptides and polynucleotides for diagnosis and treatment in receptor- mediated disorders. The invention further relates to methods using the receptor polypeptides and polynucleotides to identify agonists and antagonists useful for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the receptor polypeptides and polynucleotides. The invention further relates to procedures for producing the receptor polypeptides and polynucleotides by recombinant methods.

L'invention concerne un récepteur nouvellement identifié couplé à la protéine G. Elle concerne également des polynucléotides codant ces récepteurs. Elle concerne, de plus, des procédés mettant en application des polypeptides et des polynucléotides de ce récepteur dans le diagnostic et le traitement de maladies dans lesquelles ce récepteur joue un rôle d'intermédiaire. Elle concerne des procédés mettant en application les polypeptides et les polynucléotides de ce récepteur afin d'identifier des agonistes et des antagonistes utiles pour un diagnostic et un traitement. Elle concerne des agonistes et des antagonistes basés sur les polypeptides et les polynucléotides de ce récepteur. Elle concerne enfin des procédés de recombinaison servant à obtenir ces polypeptides et ces polynucléotides.

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