G protein-coupled receptor resembling galanin receptors

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07K 14/72 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2364988

Human and rat DNAs encoding a novel G-protein coupled receptor, GPR54, as well as proteins encoded by the DNAs, are provided. Methods of identifying agonists and antagonists of GPR54 are also provided.

La présente invention concerne des ADN humains et murins codant un nouveau récepteur, le GPR54, couplé à une protéine G, ainsi que des protéines codées par ces ADN. En outre, cette invention concerne des procédés d'identification d'agonistes et d'antagonistes de GPR54.

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