G-protein coupled receptors and nucleic acids encoding same

Details G-protein coupled receptors and nucleic acids encoding same G-protein coupled receptors and nucleic acids encoding same

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2404541

Disclosed herein are nucleic acid sequences that encode G-coupled protein- receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention concerne des séquences d'acides nucléiques codant pour des polypeptides associés aux récepteurs couplés aux protéines G. L'invention concerne également des polypeptides codés par ces séquences d'acides nucléiques et des anticorps se liant de manière immunospécifique à ce polypeptide, ainsi que des dérivés, variants, mutants ou fragments du polypeptide, du polynucléotide ou de l'anticorps susmentionné. Elle se rapporte en outre à des méthodes de traitement, de diagnostic et de recherche destinées à diagnostiquer, traiter et prévenir les troubles impliquant ces nouveaux acides nucléiques humains ou ces protéines.

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