G-proteins coupled receptor related polypeptides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2401453

Disclosed herein are nucleic acid sequences that encode G-coupled protein- receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, of fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention concerne des séquences nucléotidiques codant des polypeptides apparentés aux protéines récepteurs couplées à la protéine G. L'invention concerne également des polypeptides codés par ces séquences, et des anticorps, capables de liaison immunospécifique avec le polypeptide, ainsi que des dérivés, des variants, des mutants, ou des fragments de polypeptide, de polynucléotide ou d'anticorps susmentionné. L'invention concerne en outre des procédés thérapeutiques, diagnostiques et de recherche pour le diagnostic, le traitement et la prévention des troubles associés à ces protéines et acides nucléiques humains.

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