G12l, a gene associated with the thermal response

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2401173

Disclosed herein are novel human and mouse nucleic acid sequences that encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel nucleic acids and proteins.

La présente invention concerne de nouvelles séquences d'acide nucléique d'homme et de souris codantes pour des polypeptides. Cette invention concerne aussi des polypeptides codés par ces séquences d'acide nucléique, et des anticorps qui se lient de façon immunospécifique à ce polypeptide, de même que des dérivés, des variants, des mutants ou des fragments des polypeptides, des polynucléotides ou des anticorps susmentionnés. Cette invention concerne enfin des techniques de thérapie, de diagnostic et de recherche destinées au diagnostic, au traitement et à la prévention de pathologies dans lesquelles un de ces acides nucléiques ou une de ces protéines sont impliqués.

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