C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2109193
The present invention relates to a stably co-transfected eukaryotic cell line capable of expressing a GABA A receptor, particularly a human GABA A receptor, which receptor comprises at least one alpha, one beta and one gamma subunit; to the cloning of novel cDNA sequences encoding the a2, a3, a5, a6 and .beta.2 subunits of the human GABA A receptor; and to the use of the cell line in designing and developing GABA A receptor subtype-selective medicaments.
Hadingham Karen L.
Le Bourdelles Beatrice
Whiting Paul J.
Wingrove Peter B.
Gowling Lafleur Henderson Llp
Merck Sharp & Dohme Limited
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