Gaba uptake inhibitors having a pyrrolidine structure

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 207/16 (2006.01) A61K 31/40 (2006.01) A61K 31/401 (2006.01) A61K 31/4015 (2006.01) A61P 25/00 (2006.01) C07D 207/08 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2343531

The invention relates to compounds of general formula (I) wherein R1 to R7, A1, A2, X and Z are defined as in Claim No. 1. These compounds are suited as GABA uptake inhibitors for treating diseases such as epilepsy.

L'invention concerne des composés de la formule générale (I) dans laquelle R?1¿ à R?7¿, A?1¿, A?2¿, X et Z ont la signification mentionnée dans la description. Ces composés s'utilisent comme inhibiteurs d'absorption de GABA pour traiter des affections telles que par exemple l'épilepsie.

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