C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61P 25/00 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2535406
This invention relates to the use of compounds of benzoindazole derivatives salts and solvates thereof for the preparation of a medicament for modulating alpha2 subtype GABA A receptors. The invention further relates to novel heterocyclic compounds and pharmaceutical compositions containing said compounds. In addition the invention relates to the use of compounds of formula (I) salts and solvates thereof for the preparation of a medicament for the treatment of depression, an anxiety disorder, a psychiatric disorder, a learning or cognitive disorder, a sleep disorder, a convulsive or seizure disorder or pain.
La présente invention concerne l'utilisation de sels de dérivés de benzoindazole et de solvates de ces derniers dans la préparation d'un médicament permettant de moduler les récepteurs GABA A du sous-type alpha2. L'invention concerne en outre de nouveaux composés hétérocycliques et des compositions pharmaceutiques desdits composés. L'invention porte également sur l'utilisation de composés de sels de la formule I et de solvates de ces derniers dans la préparation d'un médicament destiné au traitement de la dépression, des troubles anxieux, des troubles psychiatriques, des troubles de l'apprentissage ou des troubles cognitifs, des troubles du sommeil, des troubles convulsifs ou épileptiques ou des douleurs.
Lin Xiao-Fa
Loughhead David Garrett
Novakovic Sanja
O'yang Counde
Putman David George
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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