Galactose-alpha-1, 3-galactose-containing n-glycans in...

G - Physics – 01 – N

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G01N 33/68 (2006.01)

Patent

CA 2749281

The present invention provides methods for evaluating a Chinese Hamster Ovary (CHO) cell population by mea-suring glycans containing terminal galactose-alpha-1-3-galactose residues produced by said cells, wherein the CHO cells have not been genetically engineered to express an alpha-galactosyl transferase coding sequence.

La présente invention concerne des méthodes d'évaluation d'une population de cellules CHO (Chinese Hamster Ovary) par mesure des glycanes contenant des résidus galactose-alpha-1-3-galactose terminaux produits par lesdites cellules, lesdites cellules CHO n'ayant pas été génétiquement modifiées pour exprimer une séquence codant l'alpha-galactosyle transférase.

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