Galactosyltransferase homolog, znssp11

Details Galactosyltransferase homolog, znssp11 Galactosyltransferase homolog, znssp11

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 38/45 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 9/10 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2427915

Novel soluble, and membrane bound, Betal,3 galactosyltranferase polypeptides, polynucleotides encoding the polypeptides, antibodies and related compositions and methods are disclosed. The polypeptides may be used for detecting anti- coéplementary molecules, agonists and antagonists. The polypeptides and antibodies may also be used in methods that modulase cell-cell interactions, and glycoprotein and glycolipid modifications.

L'invention concerne une nouvelle liaison membranaire soluble, des polypeptides de béta-1, 3 galactosyltranférase, des polynucléotides codant pour ces polypeptides, des anticorps, et des compositions et des méthodes associées. Lesdits polypeptides peuvent être utilisés pour détecter des molécules anti-complémentaires, des agonistes et des antagonistes. Les polypeptides et les anticorps peuvent également être utilisés dans des méthodes permettant de moduler les interactions de cellule à cellule, et des modifications glycoprotéiniques et glycolipidiques.

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