Galectin 11

Details Galectin 11 Galectin 11

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/66 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2336406

The present invention relates to novel galectin 11 proteins which are members of the galectin superfamily. In particular, isolated nucleic acid molecules are provided encoding the human galectin 11 proteins. Galectin 11 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of galectin 11 activity. Also provided are diagnostic and therapeutic methods.

On décrit de nouvelles protéines galectines 11 qui sont des membres de la superfamille des galectines. On décrit plus particulièrement des molécules d'acides nucléiques isolées qui codent les protéines galectines 11, ainsi que des polypeptides de galectine 11, des vecteurs, des cellules hôtes et des vecteurs de recombinaison utilisés pour produire ces derniers. L'invention concerne également des procédés de criblage permettant d'identifier des agonistes et des antagonistes de l'activité de la galectine 11, ainsi que des procédés de diagnostic et de thérapie.

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