A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/08 (2006.01) A61K 31/404 (2006.01) A61P 25/06 (2006.01)
Patent
CA 2713163
The invention relates to a galenic form for the oral transmucosal delivery of at least one active ingredient of the family of triptans, comprising at least: said active ingredient in base form and in salt form, and an aqueous-alcoholic solution with a titer of at least 15 degrees alcohol, said active ingredient being present in a stable and complete dissolution state in the aqueous-alcoholic solution, for rapid absorption of said active ingredient through the mucosa of the oral cavity and/or of the oropharynx. The invention also relates to a method for obtaining this galenic formulation and to the use thereof.
L'objet de l'invention estuneforme galénique pour l'administration par voie trans-muqueuse buccale d'au moins un principe actif de la famille des Triptans, comprenant au moins: ledit principe actif sous forme base et sous forme de sel, et; une solution hydroalcoolique titrant au moins 15 degrésd'alcool, ledit principe actif étant présent en état de dissolution stable et complète dans la solution hydroalcoolique, de façon à permettre une absorption rapide dudit principe actif à travers les muqueuses dela cavité buccale et/ou de l'oropharynx. L'invention concerne aussiun procédé d'obtention de cette formulation galénique ainsi queson utilisation.
Maury Marc
Perovitch Philippe
Maury Marc
Perovitch Philippe
Robic
LandOfFree
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