Galenical retard form

Details Galenical retard form Galenical retard form

A - Human Necessities

61

K

167/164, 167/229

A61K 9/10 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 9/52 (2006.01) A61K 31/44 (2006.01)

Patent

CA 1264441

Abstract Solid dispersion of a pharmacologically active agent in a crystalline matrix as a carrier , characterized by an agent which a. has a solubility of maximally 0.01% at 37°C in water, b. is present in the matrix at a concentration of more than 5 percent of weight, c. is present in the matrix at a concentration of above 5 percent by weight in a coherent crystalline form. The secondary active agent structure which results by extracting the matrix material with e.g. water. The pharmaceutical compositions containing the solid dispersion or the secondary active agent structure, which when taken orally, show a slow release of the active agent.

483768

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