Galk1s as modifiers of the pten/akt pathway and methods of use

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01)

Patent

CA 2612224

Human GALKl genes are identified as modulators of the PTEN/AKT pathway, and thus are therapeutic targets for disorders associated with defective PTEN/AKT function. Methods for identifying modulators of PTEN/AKT, comprising screening for agents that modulate the activity of GALKl are provided.

L'invention concerne des gènes humains GALKl identifiés comme modulateurs de la voie PTEN/AKT, et constituant ainsi des cibles thérapeutiques dans les troubles associés à une fonction PTEN/AKT déficiente. L'invention concerne également des méthodes d'identification des modulateurs de PTEN/AKT, comprenant le criblage d'agents modulant l'activité de GALKl.

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