A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01)
Patent
CA 2612224
Human GALKl genes are identified as modulators of the PTEN/AKT pathway, and thus are therapeutic targets for disorders associated with defective PTEN/AKT function. Methods for identifying modulators of PTEN/AKT, comprising screening for agents that modulate the activity of GALKl are provided.
L'invention concerne des gènes humains GALKl identifiés comme modulateurs de la voie PTEN/AKT, et constituant ainsi des cibles thérapeutiques dans les troubles associés à une fonction PTEN/AKT déficiente. L'invention concerne également des méthodes d'identification des modulateurs de PTEN/AKT, comprenant le criblage d'agents modulant l'activité de GALKl.
Bjerke Lynn Margaret
Blake Robert A.
Brace Arthur
Friedman Lori S.
Nieto-Bergman Susana
Bennett Jones Llp
Exelixis Inc.
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