C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/00 (2006.01) C07H 21/02 (2006.01) C07K 7/02 (2006.01) C07K 7/08 (2006.01) C07K 14/435 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2386555
The invention relates to .gamma.-carboxyglutamate containing conopeptides, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvulsant agents, as neuroprotective agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.
Cette invention concerne du .gamma.-carboxyglutamate renfermant des conopeptides, ainsi que des dérivés ou des sels pharmaceutiquement acceptables de ces conopeptides, et leur utilisation dans le traitement de troubles neurologiques et psychiatriques, sous forme par exemple d'agents anti-convulsants ou d'agents neuroprotecteurs analgésiques. L'invention concerne également des séquences d'acides nucléiques codant pour ces conopeptides et des propeptides codants, ainsi que les propeptides eux mêmes.
Garrett James E.
Jones Robert M.
Mcintosh J. Michael
Olivera Baldomero M.
Walker Craig S.
Cognetix Inc.
Gowling Lafleur Henderson Llp
University Of Utah Research Foundation
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