Gamma emitting, cck-a antagonists for pancreatic imaging

Details Gamma emitting, cck-a antagonists for pancreatic imaging Gamma emitting, cck-a antagonists for pancreatic imaging

C - Chemistry, Metallurgy

07

D

167/47, 260/240.

C07D 243/26 (2006.01) A61K 51/04 (2006.01) C07B 59/00 (2006.01) C07D 243/24 (2006.01) C07D 403/00 (2006.01)

Patent

CA 2037299

Novel radiolabeled cholecystokinin-A (CCK-A) antagonists have been developed having the general structure formula I: (see above formula) which, after intravenous injection, localize in the pancreas as a result of specific binding to CCK-A receptors. These tracers, when labeled with appropriate radiohalogens, are useful as commercial diagnostic imaging radiopharmaceuticals and radiotherapeutic drugs.

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