Gamma-emitting receptor-binding quinuclidinyl benzilates;...

Details Gamma-emitting receptor-binding quinuclidinyl benzilates;... Gamma-emitting receptor-binding quinuclidinyl benzilates;...

C - Chemistry, Metallurgy

07

D

260/152, 260/272

C07D 453/02 (2006.01) A61K 51/04 (2006.01) G01N 33/60 (2006.01)

Patent

CA 1192185

ABSTRACT Compounds of the formula: Image Wherein R is phenyl, cyclopentyl or cyclohexyl, R1 is H or lower alkyl, preferably CH3, X is in the ortho-, meta- or para- position, and is selected from the group consisting of 125I, 123I, I, 18F, 77Br, 75Br, NH2, and -N = Image , R2 is in the 2, 3 and 4 position and is selected from the group consisting of H and lower alkyl, and Z? is an anion; or free amine form thereof; methods for their production and compositions for and methods of tissue radio-assay and radio-external imaging utilizing said radioisotope containing compounds.

378963

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