Gamma-globulin preparation for intravenous administration

A - Human Necessities – 61 – K

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167/139

A61K 39/395 (2006.01) A61K 37/04 (1985.01)

Patent

CA 1211710

Abstract A dry .gamma.-globulin preparation capable of intravenous injection which is obtainable by poly- ethylene glycol fractionation of plasma is improved in its water-solubility and stability against increase of anticomplement activity and decrease of antibody titer by purifying the .gamma.-globulin fraction with respect to protein to render the residual polyethylene glycol substantially not detectable in its 5% W/V solution, adding 0.2 to 2 parts by weight of glucose based on 1 part of .gamma.-globulin, and lyophilizing its solution.

446694

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