Gamma-ketoacid tetrapeptides as inhibitors of caspase-3

Details Gamma-ketoacid tetrapeptides as inhibitors of caspase-3 Gamma-ketoacid tetrapeptides as inhibitors of caspase-3

C - Chemistry, Metallurgy

07

K

C07K 5/023 (2006.01) A61K 38/05 (2006.01) A61P 25/00 (2006.01) A61P 37/00 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2353079

The invention encompasses the novel class of compounds represented by formula I, which are caspase-3 inhibitors. The invention also encompasses certain pharmaceutical compositions for treatment of caspase-3 mediated diseases comprising compounds of formula I.

L'invention concerne une nouvelle classe de composés correspondant à la formule (I) et agissant comme des inhibiteurs de caspase-3. L'invention concerne aussi certaines compositions pharmaceutiques à médiation par caspase-3 qui comprennent des composés correspondant à la formule (I).

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