C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 271/22 (2006.01) A61K 31/27 (2006.01) A61P 25/28 (2006.01) C07D 243/10 (2006.01) C07D 243/14 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2397543
Gamma-secretase inhibitors, useful in the treatment or prevention of Alzheimer's disease, are disclosed. The preferred compounds have, as the central portion of the molecule, the structure (a) and are diastereoisomers of known protease inhibitors.
L'invention concerne des inhibiteurs de la gamma-secrétase, utiles dans le traitement ou la prévention de la maladie d'Alzheimer. Les composés préférés présentent, comme portion centrale de la molécule, la structure (a) et sont des diastéréoisomères d'inhibiteurs de protéase connus.
Castro Pineiro Jose Luis
Harrison Timothy
Hunt Peter Alan
Nadin Alan John
Merck Sharp And Dohme Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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