Gamma secretase modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/10 (2006.01) A61K 31/4162 (2006.01) A61K 31/4245 (2006.01) A61P 25/28 (2006.01) C07D 471/04 (2006.01) C07D 498/04 (2006.01) C07D 498/20 (2006.01)

Patent

CA 2742317

In its many embodiments, the present invention provides novel heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.

Dans ses nombreux modes de réalisation, la présente invention concerne de nouveaux composés hétérocycliques en tant que modulateurs de sécrétase gamma, des procédés de préparation de tels composés, des compositions pharmaceutiques contenant un ou plusieurs de tels composés, des procédés de préparation de formulations pharmaceutiques comprenant un ou plusieurs de tels composés, et des procédés de traitement, prévention, inhibition, ou amélioration dune ou plusieurs maladies associées au système nerveux central en utilisant de tels composés ou compositions pharmaceutiques.

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