C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/04 (2006.01) A61K 31/5395 (2006.01) A61K 31/553 (2006.01) A61P 25/28 (2006.01) C07D 413/10 (2006.01) C07D 498/10 (2006.01) C07D 498/14 (2006.01)
Patent
CA 2742472
In its many embodiments, the present invention provides a novel class of heterocyclic compounds of the formula: as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.
La présente invention concerne, dans bon nombre de ses aspects, une nouvelle classe de composés hétérocycliques de formule : en tant que modulateurs de gamma sécrétase, des procédés de préparation de ces composés, des compositions pharmaceutiques contenant un ou plusieurs de ces composés, des procédés de préparation de formulations pharmaceutiques contenant un ou plusieurs de ces composés, et des méthodes de traitement, de prévention, d'inhibition, ou d'amélioration d'une ou plusieurs maladies touchant le système nerveux central à l'aide de ces composés ou compositions pharmaceutiques.
Bennett Chad E.
Burnett Duane A.
Cole David James
Dhondi Pawan Kumar
Greenlee William J.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
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