Gamma secretase modulators

Details Gamma secretase modulators Gamma secretase modulators

C - Chemistry, Metallurgy

07

D

C07D 413/10 (2006.01) A61K 31/4245 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) C07D 413/14 (2006.01) C07D 498/04 (2006.01) C07D 498/10 (2006.01) C07D 498/20 (2006.01)

Patent

CA 2686589

In its many embodiments, the present invention provides a novel class of heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.

Dans beaucoup de ses modes de réalisation, la présente invention concerne une nouvelle classe de composés hétérocycliques comme modulateurs de gamma sécrétase, des procédés de préparation de tels composés, des compositions pharmaceutiques contenant un ou plusieurs de ces composés, des procédés de préparation de formulations pharmaceutiques comprenant un ou plusieurs de ces composés et des procédés de traitement, de prévention, d'inhibition ou d'amélioration d'une ou plusieurs maladies associées au système nerveux central utilisant de tels composés ou des compositions pharmaceutiques.

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