C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/40 (2006.01) A61K 31/00 (2006.01) A61P 25/28 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2707492
The present invention provides compounds that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
La présente invention concerne des composés qui sont des modulateurs de la gamma-sécrétase et qui sont, par conséquent, utiles pour le traitement de maladies, comme la maladie d'Alzheimer, qui peuvent être traitées par modulation de la gamma-sécrétase. L'invention concerne également des compositions pharmaceutiques qui contiennent de tels composés et des procédés de préparation de tels composés.
Adams Jeffrey A.
Amegadzie Albert
Chavez Frank Jr.
Chen Jian J.
Chen Ning
Amgen Inc.
Gowling Lafleur Henderson Llp
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