C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/10 (2006.01) A23L 1/29 (2006.01) A23L 1/30 (2006.01) A61K 31/7028 (2006.01) A61K 31/7032 (2006.01)
Patent
CA 2489456
The invention relates to a ganglioside mixture, containing of consisting of gangliosides, of the following general formula: (sugar)-OCH~2-CH(-NH-CO-R1~)- CH(OH)-CH=CH-R2~, wherein (sugar) represents a sugar radical, the group -CO- R1~ represents an acyl-fatty acid which is bonded to the radical of the molecule in the form of an amide, Rl~ represents a straight, saturated alkyl radical having at least 10 C-atoms and R2~ represents a straight, saturated alkyl radical having at least 10 C-atoms or a straight alkenyl radical having at least 10 C-atoms and one, two or three double bond(s). Said mixture is characterised in that at least 10 wt. % of the gangliosides of the general formula I are of the group -CO-R1~ and the acyl-fatty acids are a C20:0 fatty acid. Said mixtures exhibit an improved biological activity.
L'invention concerne un m~lange de gangliosides de la formule g~n~rale (I) suivante: (sucre)-OCH´2?-CH(-NH-CO-R?1´)-CH(OH)-CH=CH-R?2´, dans laquelle (sucre) repr~sente un radical sucre, le groupe -CO-R?1´ repr~sente un acide gras acyl~ qui, sous la forme d'un amide, est li~ au radical de la mol~cule, R?l´ repr~sente un radical alkyle satur~ comportant au moins dix atomes de carbone et R?2´ repr~sente ou contient les ~l~ments suivants ou est constitu~ des ~l~ments suivants: un radical alkyle satur~ lin~aire comportant au moins dix atomes de carbone ou un radical alc~nyle lin~aire et une, deux ou trois liaison(s) double(s). Ce m~lange est caract~ris~ en ce que, parmi les gangliosides pr~sents de la formule g~n~rale (I), au moins 10 % en poids du groupe -CO-R?1´ et par cons~quent des acides gras acyl~s sont un acide gras C20:0. Ces m~langes pr~sentent une activit~ biologique am~lior~e.
Beermann Christopher
Bode Lars
Boehm Gunther
N.v. Nutricia
Ridout & Maybee Llp
LandOfFree
Gangliosides with a modified acyl function does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Gangliosides with a modified acyl function, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gangliosides with a modified acyl function will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2021624