Gankyrin

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/21 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2305814

A gankyrin having the amino acid sequence specified in SEQ ID NO: 2; a modified gankyrin which has an amino acid sequence formed by modifying the amino acid sequence specified in SEQ ID NO: 2 by deletion, addition, and/or substitution by other amino acid of one or more amino acids and maintains the biological activity of the gankyrin; a gene coding for the gankyrin or the modified gankyrin; and the production process and use of said proteins.

L'invention concerne une gankyrine comprenant la séquence d'acide aminé décrite dans SEQ ID NO:2; une gankyrine modifiée qui présente une séquence d'acides aminés obtenue par modification de la séquence d'acides aminés spécifiée dans SEQ ID NO:2, au moyen d'une délétion, d'une addition et/ou d'une substitution d'un ou de plusieurs acides aminés par d'autres acides aminées. Cette gankyrine modifiée conserve l'activité biologique de la gankyrine. L'invention concerne également un gène codant pour la gankyrine ou la gankyrine modifiée, et le procédé permettant de produire ces protéines.

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