Gas and oxygen carrying lipid vesicles

Details Gas and oxygen carrying lipid vesicles Gas and oxygen carrying lipid vesicles

B - Operations, Transporting

01

J

B01J 13/02 (2006.01) A61K 8/14 (2006.01) A61K 9/00 (2006.01) A61K 9/127 (2006.01) A61K 49/22 (2006.01) B01J 13/12 (2006.01) B01J 13/18 (2006.01) B01J 13/20 (2006.01)

Patent

CA 2106405

2106405 9215284 PCTABS00016 The present invention relates to the production of lipid vesicles having a moderately volatile material such as a perfluorocarbon or a silicone oil encapsulated therein. In another aspect, lipid vesicles having a gas-filled center or core are made. The lipid vesicles having gas-filled central core are made by dehydrating vesicles having the moderately volatile liquid encapsulated in the central core. This drives off the water first, allowing the moderately volatile liquid to stabilize the vesicle structure as it dries, finally forming a central void which can refract light. The preferred vesicles of the invention are paucilamellar vesicles.

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