Gas filled liposomes and their use as ultrasonic contrast...

A - Human Necessities – 61 – K

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A61K 49/00 (2006.01) A61K 9/127 (2006.01) A61K 41/00 (2006.01) A61K 47/48 (2006.01) A61K 49/18 (2006.01) A61K 49/22 (2006.01) B01J 13/02 (2006.01)

Patent

CA 2110491

Contrast agents for ultrasonic imaging comprising gas filled liposomes prepared using vacuum drying gas instillation methods, and gas filled liposomes substantially devoid of liquid in the interior thereof, are described. Methods of and apparatus (1-19) for preparing such liposomes and methods for employing such liposomes in ultrasonic imaging applications are also dis-closed. Also described are diagnostic kits for ultrasonic imaging which include the subject contrast agents.

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