Gas-filled microspheres as novel therapeutic delivery...

A - Human Necessities – 61 – K

Patent

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A61K 9/127 (2006.01) A61K 9/16 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 41/00 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) A61K 49/18 (2006.01) A61K 49/22 (2006.01) A61N 2/00 (2006.01) A61N 5/00 (2006.01) A61N 7/00 (2006.01) B01J 13/02 (2006.01) A61M 5/31 (2006.01)

Patent

CA 2164846

Therapeutic delivery systems comprising gaseous precursor-filled microspheres comprising a therapeutic are described. Methods for employing such microspheres in therapeutic delivery applications are also provided. Therapeutic delivery systems comprising gaseous precursor-filled liposomes having encapsulated therein a contrast agent or drug are preferred. Methods of and apparatus for preparing such liposomes and methods for employing such liposomes in therapeutic delivery applications are also disclosed.

Système d'administration de produits thérapeutiques comportant des microsphères remplies d'un précurseur gazeux comportant un produit thérapeutique et procédé d'administration de produits thérapeutiques au moyen de ces microsphères. Les systèmes utilisant des liposomes remplis d'un précurseur gazeux où se trouve encapsulé un agent de contraste ou un médicament sont préférés. Sont également présentés des méthodes et moyens de préparation desdits liposomes et leurs méthodes d'administration dans des applications thérapeutiques.

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