Gas-filled microspheres with fluorine-containing shells

A - Human Necessities – 61 – K

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Details

A61K 49/00 (2006.01) A61K 49/22 (2006.01)

Patent

CA 2196599

Improved ultrasonic imaging contrast agents are provided which are comprised of an aqueous suspension of microspheres comprising at least one gas, preferably a perfluorocarbon, encapsulated by elastic shells of a biocompatible, fluorine-containing amphiphilic material, processes for making the microspheres, and methods of diagnostic imaging using the improved contrast agents.

Agents de contraste pour imagerie par ultrasons faits d'une suspension aqueuse de microsphères comprenant au moins un gaz (de préférence un perfluocarbone) encapsulé dans des enveloppes élastiques biocompatibles d'un produit amphiphilique à base de fluor; procédés d'élaboration desdites microsphères; et méthodes de diagnostic par imagerie recourant auxdits agents.

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