Gastric acid secretion inhibiting substituted 2-(2-...

Details Gastric acid secretion inhibiting substituted 2-(2-... Gastric acid secretion inhibiting substituted 2-(2-...

C - Chemistry, Metallurgy

07

D

260/277.7

C07D 401/12 (2006.01) C07D 213/04 (2006.01) C07D 235/28 (2006.01)

Patent

CA 1129417

ABSTRACT The present invention relates to novel compounds of the formula Image and salts thereof, wherein R1 and R2 are the same or different and are each hydrogen, alkyl, halogen, carbomethoxy, carbethoxy, alkoxy, or alkanoyl, R6 is hydrogen, methyl or ethyl, R3, R4 and R5 are same or different and are each hydrogen, methyl, methoxy, ethoxy, methoxyethoxy or ethoxyethoxy with the pro- viso that R3, R4 and R5 are not all hydrogen, and the further proviso that when two of R3, R4 and R5 are hydrogen the third of R3, R4 and R5 is not methyl. The compounds can be oxidized to the corresponding sulfinyl compounds which are potent gastric acid se- cretion inhibitors.

386943

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