Gastrointestinal mucosa-adherent pharmaceutical composition

Details Gastrointestinal mucosa-adherent pharmaceutical composition Gastrointestinal mucosa-adherent pharmaceutical composition

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 31/29 (2006.01) A61K 31/381 (2006.01) A61K 31/42 (2006.01) A61K 31/422 (2006.01) A61K 31/43 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/67 (2006.01) A61K 31/675 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2282531

In order to provide a composition having a long gastroduodenal residence time and exhibiting an improved efficacy, is provided a gastrointestinal mucosa- adherent composition comprising an active ingredient and a material which swells a viscogenic agent capable of being viscous with water (e.g. curdlan and/or a low-substituted hydroxypropylcellulose, etc.).

Pour obtenir une composition à long temps de séjour gastro-duodénal d'une efficacité renforcée, on a mis au point une composition adhérant à la muqueuse gastro-intestinale comportant un principe actif et une substance faisant gonfler un agent viscogène devenant visqueux en présence d'eau tel que par exemple du curdlan et/ou de l'hydroxypropyle cellulose faiblement substituée, etc.

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