G - Physics – 21 – H
Patent
G - Physics
21
H
167/47
G21H 5/02 (2006.01) A61K 49/00 (2006.01) A61K 51/12 (2006.01) G01T 1/164 (2006.01)
Patent
CA 1124175
GASTROINTESTINAL SCANNING AGENT Abstract Technetium-99m has ideal characteristics for im- aging the upper and lower GI tract and determining stomach emptying and intestinal transit time when used with an insoluble particulate material. For example, crystalline and amorphous calcium phosphate particles can be effectively labeled in a one-step process using 99mTcO4 and SnC12. These labeled particles have insignificant mass and when administered orally pass through the GI tract unchanged, without affecting the handling and density of the in- testinal contents. Visualization of the esophageal entry into the stomach, -the greater and lesser curvatures of the stomach, ejection into the duodenum, and rates of passage through the upper and lower GI tract are obtained. The slurry of 99mTc particulate can be given rectally by enema. Good images of the cecum and the ascending, transverse, and descending colon are obtained. Mucusal folds and the splenic and hepatic flexures are visualized The resilience of the large intestine is also readily visualized by pneumocolonographic techniques.
331771
Kirby Eades Gale Baker
The Procter & Gamble Company
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