Gastroresistant pharmaceutical formulations containing...

Details Gastroresistant pharmaceutical formulations containing... Gastroresistant pharmaceutical formulations containing...

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 31/395 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2595033

The object of the invention consists of pharmaceutical formulations containing rifaximin in the shape of microgranules made gastroresistant by an insoluble polymer at pH values between 1.5 and 4.0 and soluble at pH values between 5.0 and 7.5, by their preparation and by their use in the manufacture of medicinal preparations useful in the treatment of inflammatory bowel diseases (IBD) and mainly Crohn's disease.

La présente invention concerne des formulations pharmaceutiques à base de rifaximine sous forme de microgranules rendues gastrorésistantes par un polymère insoluble à des valeurs de pH entre 1.5 et 4.0, et soluble à des valeurs de pH entre 5.0 et 7.5, par leur élaboration et leur utilisation dans la fabrication de préparations médicinales convenant au traitement d'affections intestinales inflammatoires, essentiellement la maladie de Crohn.

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