Gdnf derived peptides

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/00 (2006.01) A61K 38/18 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2619017

The present invention relates to peptide fragments derived from the proteins belonging to the TGFbeta superfamily, pharmaceutical compositions comprising said peptide fragments and uses thereof for treatment of a disease or condition wherein the effects of stimulating neuronal cell differentiation, neuronal cell survival, stimulating neural plasticity associated with learning and memory and/or inhibiting inflammatory response are beneficial for treatment.

La présente invention pour sur des fragments de peptides dérivés des protéines appartenant à la superfamille TGF-bêta, sur des compositions pharmaceutiques renfermant ces fragments de peptides et sur des utilisations de ceux-ci dans le traitement d'une maladie ou d'un état, les effets de la stimulation de la différenciation des cellules neuronales, la survie des cellules neuronales, la stimulation de la plasticité neurale associée à l'apprentissage et à la mémoire et/ou l'inhibition de la réponse inflammatoire étant bénéfiques au traitement.

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