Gel composition and methods

Details Gel composition and methods Gel composition and methods

A - Human Necessities

61

K

A61K 9/10 (2006.01) A61K 47/02 (2006.01) A61K 47/08 (2006.01) A61K 47/14 (2006.01) A61K 47/34 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2591581

Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, compositions having burst indices of 8 or less for systemic applications and systems releasing 10 % or less of the total dose of beneficial agent in the first 24 hours after implantation for local applications. The compositions include a biocompatible polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.

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