A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4164 (2006.01) A61K 9/08 (2006.01) A61K 47/22 (2006.01) A61K 47/40 (2006.01) A61P 17/10 (2006.01)
Patent
CA 2405072
An aqueous solution of metronidazole in which the concentration of metronidazole is higher than 0.75 %. The solution contains the solubility enhancer hydroxypropyl-betacyclodextrin and may additionally contain niacinamide. Methods of manufacture and therapeutic use of the solution are disclosed. Image
L'invention concerne une solution aqueuse de métronidazole dans laquelle la concentration de métronidazole est supérieure à 0,75 %. La solution renferme de l'hydroxypropyl-bétacyclodextrine, qui renforce la solubilité, et éventuellement aussi de la niacinamide. L'invention concerne également des procédé relatifs à la fabrication et à l'utilisation thérapeutique de la solution.
Angel Arturo
Chang Yunik
Dow Gordon J.
Dow Pharmaceutical Sciences
Oyen Wiggs Green & Mutala Llp
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