A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/38 (2006.01) A61K 47/06 (2006.01) A61K 47/10 (2006.01) A61K 47/16 (2006.01) A61K 47/18 (2006.01) A61K 47/30 (2006.01) A61K 47/32 (2006.01)
Patent
CA 2281919
Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative disease. In the subject methods, antiproliferative agents are administered in a substantially non-aqueous gel delivery vehicle comprising at least one polar organic solvent in combination with one or more thickening agents. The subject methods and compositions provide for the enhanced efficacy of regionally or locally administered antiproliferative proliferative agents.
La présente invention concerne des procédés et des compositions permettant de traiter un hôte souffrant d'une maladie de prolifération cellulaire. Dans lesdits procédés, on administre des agents antiprolifératifs dans un véhicule d'administration se présentant sous forme de gel sensiblement non aqueux et comprenant au moins un solvant organique polaire en combinaison avec un ou plusieurs agents épaississants. Les dits procédés et compositions présentent une efficacité améliorée des agents s'opposant à la prolifération cellulaire, administrés de manière locale ou régionale.
Jones Richard E.
Maskiewicz Richard
Roskos Kathleen V.
Trager George
Washco Keith
Intarcia Therapeutics Inc.
Ledgley Law
Matrix Pharmaceutical Inc.
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